Magnetic Resonance Imaging I – Basic Principles and Applications
Learning Outcomes
Participants will learn the basic principles and the instrumentation of magnetic resonance imaging (MRI). Basic measurement techniques (MR-sequences) and the related image contrast mechanisms will be studied. The mathematical framework is developed to describe image encoding, the point-spread function (PSF), signal-to-noise ratio and contrast mechanism of MRI. Python exercises and homework are used to deepen the understanding of the basic concepts.
Content
History of MRI, physical principle, Nuclear Magnetic Resonance (NMR) Effect, relaxation phenomena and chemical shift, spatial localisation and imaging, k-space formalism, basic pulse sequences (gradient and spin echo), contrast manipulation, fast imaging sequences, motion compensation, instrumentation and safety, signal-to-noise ratio, image-quality, artefacts, clinical applications and research.
Lecture Schedule (20.10.2021 - 23.02.2022)
|
No. |
Who |
When |
|
What |
|
1 |
Tobias Schäffter |
20.10 |
L |
History of Biomedical Imaging and Intro MRI |
|
2 |
Tobias Schäffter |
27.10 |
L |
NMR-Effect, equation of motion, Bloch equation (homework 1) |
|
3 |
Tobias Schäffter |
3.11 |
L |
NMR Spectroscopy frequency selective excitation (homework 2), X-nuclei (H, P, C), Chemical Shift, J-coupling |
|
4 |
Sebastian Schmitter |
10.11 |
L |
Spatial Encoding I - Slice-Selective excitation, excitation k-space, rf-pulse design (homework3) |
|
5 |
Tobias Schäffter |
17.11 |
L |
Spatial Encoding II - signal equation, k-space, Magnetic Resonance Imaging, phase encoding, frequency encoding (homework 4) |
|
6 |
Tobias Schäffter |
24.11 |
L |
Relaxation, measurement of relaxation times: Spin-Echo, Inversion Recovery (homework 5) |
|
7 |
Tobias Schäffter |
1.12 |
L |
Spin-Echo and gradient echo MRI, image contrast (homework 6) |
|
8 |
Christoph Kolbitsch |
8.12 |
L |
Transient Echo |
|
9 |
Tobias Schäffter |
15.12 |
L |
Steady State, SSFP Imaging (homework 7) |
|
10 |
Tobias Schäffter |
12.01 |
L |
Fast MRI, TSE, EPI |
|
11 |
Christoph Kolbitsch |
19.01 |
E |
MRI, PSF, Contrast, Steady State (homework8) |
|
12 |
Christoph Kolbitsch |
26.01 |
L |
Phase-Diagram |
|
13 |
Tobias Schäffter |
02.02 |
L |
Image quality, SNR, Artefacts (homework9) |
|
14 |
Lukas Winter |
09.02 |
L |
Hardware, Magnet, Gradients, RF-coils, Spectrometer, SNR |
|
15 |
Lukas Winter |
16.02 |
L |
MRI Safety, SAR (homework 10) |
|
16 |
ALL |
23.02 |
|
Visit MR-Scanner RF-coil lab |
Type of portfolio examination
homework, individual examination with a written and oral part
Test elements
|
Name |
Points |
Category |
Duration/Extent |
|
Homework |
25 |
written |
report provided by groups |
|
Examination- written part |
25 |
written |
10min one exercise question (similar to homework) |
|
Examination - oral part |
50 |
oral |
20min 2-3 comprehension (MR-physics) questions (30points), 1 derivation question (MR-Physics, Math) 20 points |
Grading scale
|
1.0 |
1.3 |
1.7 |
2.0 |
2.3 |
2.7 |
3.0 |
3.3 |
3.7 |
4.0 |
|
95.0 |
90.0 |
85.0 |
80.0 |
75.0 |
70.0 |
65.0 |
60.0 |
55.0 |
50.0 |
- Trainer/in: Axel Krause
- Trainer/in: Christina Mittag
- Trainer/in: Tobias Richard Schäffter
- Trainer/in: Lukas Julius Schneidewind
- Trainer/in: Peter Seufert